RAF Typhoon FGR4s have conducted a mission with France's air force in a combined operation targeting an subterranean weapons facility in Syria employed by the Islamic State group (IS), according to the British defence ministry.
The site, located using reconnaissance, was believed to be containing munitions and bombs, the announcement noted, and was located in hills just to the north of Palmyra in the heart of Syria.
"The RAF jets used Paveway IV guided bombs to target a number of access tunnels down to the facility... initial indications suggest the objective was successfully hit," the MoD said.
There was no indication of any harm to civilians in the attack on Saturday evening and all the aircraft made a safe return, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
Daesh - referred to as ISIS - established militant control over significant areas in both Syria and Iraq before its territorial defeat in 2019.
"This action shows the UK's leading role, and resolve to operate in unison with allied nations, to eliminate any re-emergence of IS and their harmful and extremist ideologies in the Middle East," the British Defence Secretary John Healey stated.
UK warplanes have conducted patrols over Syrian airspace to "forestall any efforts to regroup" of IS following its defeat at the climactic battle in Baghuz in the year 2019, the MoD reported.
"I want to thank the personnel of British forces involved in this operation for their expertise and their bravery," the Defence Secretary said. "Including them were a great many British troops stationed over Christmas and New Year. This action, to eliminate dangerous terrorists who endanger our safety, shows how our armed forces are always on standby, throughout the year, protecting the UK within its borders and influential overseas."
Last December, the US military conducted what it described as a "massive strike" against Islamic State objectives in the country, after an assault killed two US servicemembers and a local interpreter in Palmyra.
The UN estimates Islamic State still boasts roughly 5-7 thousand fighters in both countries.